Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.34 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002238 | 0.88 | CACNA1B (0.40) | MAPK1SMN1; SMN2SERPINE1PTPN1ECE1 | |
| SCHEMBL6002334 | 0.88 | SMN1; SMN2 (0.39) | MAPK1SMN1; SMN2SERPINE1PTPN1PTGDR2 | |
| SCHEMBL6002292 | 0.86 | SERPINE1 (0.48) | SERPINE1CCR2ECE1 | |
| SCHEMBL6001713 | 0.84 | SERPINE1 (0.49) | MAPK1SMN1; SMN2SERPINE1CCR2ECE1 | |
| SCHEMBL6001802 | 0.83 | MAPK1 (0.43) | MAPK1SMN1; SMN2SERPINE1PTPN1PTGDR2 | |
| SCHEMBL6001817 | 0.83 | MAPK1 (0.43) | MAPK1SMN1; SMN2PTPN1CA2PTPN11 | |
| SCHEMBL6002233 | 0.83 | ECE1 (0.43) | MAPK1SMN1; SMN2ECE1EPHX2 | |
| SCHEMBL6001895 | 0.79 | POLB (0.47) | MAPK1SMN1; SMN2SERPINE1ECE1 | |
| SCHEMBL6001804 | 0.79 | L3MBTL1 (0.34) | PTGDR2L3MBTL1 | |
| SCHEMBL6001840 | 0.76 | CACNA1B (0.40) | MAPK1SMN1; SMN2ECE1PTPN11EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212296-B9 | PHOSPHATE MIMICS AND METHODS OF TREATMENT USING PHOSPHATASE INHIBITORS | SUGEN INC (US) | 2006-05-10 | — | — | EP | claimed |
| EP-1212296-B1 | PHOSPHATE MIMICS AND METHODS OF TREATMENT USING PHOSPHATASE INHIBITORS | SUGEN INC (US) | 2005-11-09 | — | — | EP | claimed |