Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002629 | 0.83 | NPSR1 (0.34) | ATMTDP1L3MBTL1NR1H3NPSR1 | |
| SCHEMBL26622112 | 0.71 | ATM (0.37) | ATMTDP1L3MBTL1NPSR1MEN1 | |
| SCHEMBL6002568 | 0.68 | TACR1 (0.30) | TACR1 | |
| SCHEMBL17681708 | 0.68 | ALDH1A1 (0.41) | ATMTDP1L3MBTL1NPSR1MEN1 | |
| SCHEMBL6002286 | 0.67 | L3MBTL1 (0.61) | ATMTDP1L3MBTL1NPSR1MEN1 | |
| SCHEMBL5170181 | 0.66 | NPSR1 (0.40) | ATMTDP1L3MBTL1NR1H3NPSR1 | |
| SCHEMBL514386 | 0.64 | SMN1; SMN2 (0.53) | L3MBTL1NPSR1MEN1RAB9AKMT2A | |
| SCHEMBL8084617 | 0.64 | CES1 (0.39) | ATMTDP1L3MBTL1NR1H3NPSR1 | |
| SCHEMBL17681664 | 0.64 | KMT2A (0.38) | ATMTDP1L3MBTL1NR1H3NPSR1 | |
| SCHEMBL6012131 | 0.64 | NPSR1 (0.38) | ATMTDP1L3MBTL1NR1H3NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |