Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002629 | 0.71 | NPSR1 (0.34) | TACR1 | |
| SCHEMBL6002979 | 0.69 | ELANE (0.32) | — | |
| SCHEMBL6002564 | 0.68 | ATM (0.33) | TACR1 | |
| SCHEMBL1335024 | 0.67 | KMT2A (0.38) | — | |
| SCHEMBL4634276 | 0.67 | ALDH1A1 (0.38) | — | |
| SCHEMBL621536 | 0.66 | L3MBTL1 (0.39) | — | |
| SCHEMBL11036085 | 0.65 | CYP2C9 (0.33) | — | |
| SCHEMBL31723993 | 0.63 | NR1H3 (0.46) | — | |
| SCHEMBL3486119 | 0.63 | CES1 (0.37) | — | |
| SCHEMBL9033853 | 0.63 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |