Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | ACP3 | P15309 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2980266 | 1.00 | KMT2A (0.39) | KMT2ATHRBCYP3A4EPHX1ACP3 | |
| SCHEMBL27822368 | 0.80 | CA1 (0.42) | KMT2AACP3ALDH1A1GAATSHR | |
| SCHEMBL6003200 | 0.80 | ADRA2A (0.35) | KMT2ATHRBALDH1A1LMNAADRA2A | |
| SCHEMBL26689 | 0.79 | KMT2A (0.44) | KMT2ATHRBEPHX1IDO1TDO2 | |
| SCHEMBL27775233 | 0.79 | THRB (0.38) | KMT2ATHRBCYP3A4EPHX1IDO1 | |
| SCHEMBL7292294 | 0.79 | L3MBTL1 (0.41) | KMT2ALMNAL3MBTL1 | |
| SCHEMBL28489517 | 0.78 | AOC3 (0.44) | CYP3A4ALDH1A1L3MBTL1 | |
| SCHEMBL7644220 | 0.78 | SLC6A4 (0.36) | KMT2ALMNAADRA2AADRA2CTSHR | |
| SCHEMBL8698025 | 0.77 | LMNA (0.37) | KMT2AALDH1A1LMNAADRA2AADRA2C | |
| SCHEMBL1129750 | 0.77 | CYP3A4 (0.49) | KMT2ACYP3A4ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1635 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3714893-A1 | CHEMICAL CROSSLINKERS | Amicus Therapeutics, Inc. (US) | 2020-09-30 | — | — | EP | claimed |
| CN-111187281-A | Cephalosporin derivative containing guanidyl and preparation method thereof | 广西科技大学 | 2020-05-22 | — | — | CN | claimed |
| EP-2976092-B1 | CHEMICAL CROSSLINKERS | AMICUS THERAPEUTICS INC (US) | 2020-04-22 | — | — | EP | claimed |
| EP-3532475-A2 | PROCESS FOR THE PREPARATION OF PYRAZOLO[1,5-a]PYRIMIDINES AND SALTS THEREOF | Array Biopharma Inc. (US) | 2019-09-04 | — | — | EP | claimed |
| WO-2019005796-A1 | PROCESS FOR THE PREPARATION OF PYRAZOLO[1,5-a]PYRIMIDINES AND SALTS THEREOF | ZHAO QIAN (US) | 2019-01-03 | — | — | WO | claimed |
| WO-2018081417-A2 | PROCESS FOR THE PREPARATION OF PYRAZOLO[1,5-a]PYRIMIDINES AND SALTS THEREOF | ZHAO QIAN (US) | 2018-05-03 | — | — | WO | claimed |
| CN-107530259-A | Method using acid amides, acid or ester C glycosides derivatives processing keratin material and the cosmetic composition containing them | 莱雅公司 | 2018-01-02 | — | — | CN | claimed |
| CN-104829632-B | A kind of cephalosporins derivatives of the substituent containing aminodithioformic acid | 中山大学 | 2017-09-29 | — | — | CN | claimed |
| CN-104530417-B | A kind of multiple functionalized H types polyethyleneglycol derivative and preparation method thereof | 厦门赛诺邦格生物科技股份有限公司 | 2017-09-08 | — | — | CN | claimed |
| CN-104530415-B | A kind of different functionalization Y types polyethyleneglycol derivative, preparation method and its bio-related substance | 厦门赛诺邦格生物科技股份有限公司 | 2017-09-01 | — | — | CN | claimed |
| WO-1994018329-A2 | SERINE PROTEASE VARIANTS HAVING PEPTIDE LIGASE ACTIVITY | GENENTECH, INC. (US) | 1994-08-18 | — | — | WO | claimed |
| US-5319080-A | Antiviral agents | CIBA-GEIGY CORPORATION (US) | 1994-06-07 | — | — | US | claimed |
| EP-0583338-A1 | METHOD FOR SYNTHESIZING PEPTIDES, NOVEL AMINO ACID DERIVATIVES USED THEREIN, AND METHODS FOR PREPARING SAME. | PROPEPTIDE SA (FR) | 1994-02-23 | — | — | EP | claimed |
| US-5166341-A | Selective antagonist of serotonin 3(5-HT3) receptor | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1992-11-24 | — | — | US | claimed |
| WO-1992019643-A1 | METHOD FOR SYNTHESIZING PEPTIDES, NOVEL AMINO ACID DERIVATIVES USED THEREIN, AND METHODS FOR PREPARING SAME | PROPEPTIDE (FR) | 1992-11-12 | — | — | WO | claimed |
| EP-0301877-A1 | A method of deprotection of 3-amino azetidinones | ELI LILLY AND COMPANY (US) | 1989-02-01 | — | — | EP | claimed |
| EP-0268963-A1 | Benzazolylthio-carbapenem antibiotics | BAYER AG (DE) | 1988-06-01 | — | — | EP | claimed |
| EP-0053962-B1 | CEPHALOSPORIN DERIVATIVES AND THEIR PREPARATION | RHONE-POULENC SANTE (FR) | 1985-03-13 | — | — | EP | claimed |
| US-4393228-A | THIOL PROTEASE INHIBITORS, ANTIINFLAMMATORY | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1983-07-12 | — | — | US | claimed |
| US-4180571-A | Arylmalonamido-1-oxadethiacephalosporins | SHIONOGI & CO., LTD. (JP) | 1979-12-25 | — | — | US | claimed |