Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | PTPRC | P08575 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29383458 | 0.72 | MAOA (0.56) | AHRMAOAMAOBALOX5TRPA1 | |
| SCHEMBL15613 | 0.72 | — | — | |
| SCHEMBL125113 | 0.72 | MAOA (0.56) | AHRMAOAMAOBALOX5TRPA1 | |
| SCHEMBL3102452 | 0.72 | MAOA (0.56) | AHRMAOAMAOBALOX5TRPA1 | |
| SCHEMBL8668546 | 0.72 | MAOA (0.56) | AHRMAOAMAOBALOX5TRPA1 | |
| SCHEMBL4571011 | 0.72 | MAOA (0.56) | AHRMAOAMAOBALOX5TRPA1 | |
| SCHEMBL8671027 | 0.72 | MAOA (0.56) | AHRMAOAMAOBALOX5TRPA1 | |
| SCHEMBL29724179 | 0.72 | MAOA (0.56) | AHRMAOAMAOBALOX5TRPA1 | |
| SCHEMBL9412277 | 0.70 | CES1 (0.30) | — | |
| Water SCHEMBL1286428 | 0.69 | MAOA (0.53) | AHRMAOAMAOBALOX5TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1275649-B1 | Benzodioxinethiophene, its preparation and use | STARCK H C GMBH (DE) | 2006-03-08 | — | — | EP | disclosed |
| EP-1275649-B1 | Benzodioxinethiophene, its preparation and use | STARCK H C GMBH (DE) | 2006-03-08 | — | — | EP | disclosed |
| US-6825357-B2 | 3,4-(1',2'-BENZODIOXY)THIOPHENE MONOMERS OF GIVEN FORMULA; ELECTROCONDUCTIVE POLYMERS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-11-30 | — | — | US | disclosed |
| US-6825357-B2 | 3,4-(1',2'-BENZODIOXY)THIOPHENE MONOMERS OF GIVEN FORMULA; ELECTROCONDUCTIVE POLYMERS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-11-30 | — | — | US | disclosed |
| US-6825357-B2 | 3,4-(1',2'-BENZODIOXY)THIOPHENE MONOMERS OF GIVEN FORMULA; ELECTROCONDUCTIVE POLYMERS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-11-30 | — | — | US | disclosed |
| EP-1275649-A3 | Benzodioxinethiophene, its preparation and use | Bayer Aktiengesellschaft (DE) | 2003-11-26 | — | — | EP | disclosed |
| EP-1275649-A3 | Benzodioxinethiophene, its preparation and use | Bayer Aktiengesellschaft (DE) | 2003-11-26 | — | — | EP | disclosed |
| US-20030028024-A1 | Benzodioxinothiophenes, their preparation and use | H. C. STARCK GMBH (DE) | 2003-02-06 | — | — | US | disclosed |
| US-20030028024-A1 | Benzodioxinothiophenes, their preparation and use | H. C. STARCK GMBH (DE) | 2003-02-06 | — | — | US | disclosed |
| US-20030028024-A1 | Benzodioxinothiophenes, their preparation and use | H. C. STARCK GMBH (DE) | 2003-02-06 | — | — | US | disclosed |
| EP-1275649-A2 | Benzodioxinethiophene, its preparation and use | Bayer Aktiengesellschaft (DE) | 2003-01-15 | — | — | EP | disclosed |
| EP-1275649-A2 | Benzodioxinethiophene, its preparation and use | Bayer Aktiengesellschaft (DE) | 2003-01-15 | — | — | EP | disclosed |
| EP-1275649-A2 | Benzodioxinethiophene, its preparation and use | Bayer Aktiengesellschaft (DE) | 2003-01-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030028024-A1 | Benzodioxinothiophenes, their preparation and use | PRDX5, BROX, PRDX2 | AHR 421/4885MAOA 729/4885MAOB 515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.