SCHEMBL6003386

SCHEMBL6003386

CCC([C]c1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.45
MIF P14174 1/20 0.41
HKDC1 Q2TB90 1/20 0.36
TRPA1 O75762 1/20 0.36
TAAR1 Q96RJ0 3/20 0.35
HTR2A P28223 3/20 0.35
HRH1 P35367 2/20 0.35
AOC3 Q16853 1/20 0.35
NOS3 P29474 1/20 0.35
NOS2 P35228 1/20 0.35
KMT2A Q03164 1/20 0.35
APP P05067 1/20 0.35
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6003379 0.83 AOC3 (0.41) LMNAMIFTAAR1HTR2AHRH1
SCHEMBL1454487 0.76 LMNA (0.46) LMNAMIFHKDC1TRPA1TAAR1
SCHEMBL1434405 0.76 LMNA (0.46) LMNAMIFHKDC1TRPA1TAAR1
SCHEMBL181368 0.76 TRPA1 (0.46) LMNAMIFHKDC1TRPA1TAAR1
SCHEMBL10012532 0.76 MIF (0.52) LMNAMIFHKDC1TRPA1TAAR1
SCHEMBL8712988 0.76 LMNA (0.46) LMNAMIFHKDC1TRPA1TAAR1
SCHEMBL143452 0.76 LMNA (0.46) LMNAMIFHKDC1TRPA1TAAR1
SCHEMBL7714097 0.75 FFAR1 (0.38) AOC3KMT2ATDP1
SCHEMBL15562569 0.75 LMNA (0.39) LMNAMIFTRPA1HTR2AAPP
SCHEMBL7008514 0.73 HTR2A (0.41) LMNAMIFTRPA1TAAR1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7092608-B2 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2006-08-15 US disclosed
US-7082244-B2 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2006-07-25 US disclosed
US-20060159413-A1 POLYIMIDE OPTICAL MATERIALS, POLYIMIDE PRECURSOR SOLUTIONS AND OPTICAL WAVEGUIDE ELEMENTS KABUSHIKI KAISHA TOSHIBA (JP) 2006-07-20 US disclosed
US-20040197064-A1 Polyimide optical materials, polyimide precursor solutions and optical waveguide elements KABUSHIKI KAISHA TOSHIBA (JP) 2004-10-07 US disclosed