Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL124120 | 0.85 | CYP19A1 (0.54) | CYP19A1CRHBPCRHR2TDP1MAPT | |
| SCHEMBL125017 | 0.77 | MAPT (0.55) | CRHBPCRHR2TDP1MAPTGAA | |
| SCHEMBL6156984 | 0.75 | CRHBP (0.65) | GPR35CRHBPCRHR2TDP1MAPT | |
| SCHEMBL11024727 | 0.75 | HTT (0.63) | CYP19A1TDP1MAPTGAAMEN1 | |
| SCHEMBL124625 | 0.74 | HTT (0.63) | MAPTGAAKMT2AHTTALDH1A1 | |
| SCHEMBL11142975 | 0.74 | TDP1 (0.64) | CYP19A1TDP1MAPTGAAMEN1 | |
| SCHEMBL4614055 | 0.74 | GPR35 (0.54) | GPR35CRHBPCRHR2TDP1MAPT | |
| Hydrochloric Acid SCHEMBL11149045 | 0.73 | TDP1 (0.62) | CYP19A1TDP1MAPTGAAMEN1 | |
| SCHEMBL9638881 | 0.73 | ALDH1A1 (0.50) | GPR35TDP1MAPTMEN1KMT2A | |
| SCHEMBL18124 | 0.72 | GPR35 (1.00) | GPR35TDP1MAPTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006087195-A2 | DYE COMPOSITION COMPRISING AT LEAST ONE METHINE DYE OF PARTICULAR STRUCTURE AND PROCESS FOR IMPLEMENTATION THEREOF | L'OREAL (FR) | 2006-08-24 | — | — | WO | disclosed |