Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | POLB | P06746 | 4/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5263966 | 0.82 | KDR (0.60) | RAB9ANPC1POLBHTTSMN1; SMN2 | |
| SCHEMBL23212117 | 0.79 | NPC1 (0.52) | RAB9ANPC1POLBHTTSMN1; SMN2 | |
| SCHEMBL4036206 | 0.77 | RAB9A (0.62) | RAB9ANPC1POLBHTTSMN1; SMN2 | |
| SCHEMBL8299753 | 0.76 | TDP1 (0.68) | RAB9ANPC1POLBHTTSMN1; SMN2 | |
| SCHEMBL1198985 | 0.76 | NPC1 (0.58) | RAB9ANPC1SMN1; SMN2KMT2ATP53 | |
| SCHEMBL3096372 | 0.75 | RAB9A (0.79) | RAB9ANPC1POLBHTTSMN1; SMN2 | |
| SCHEMBL30117873 | 0.75 | RAB9A (0.79) | RAB9ANPC1POLBHTTSMN1; SMN2 | |
| SCHEMBL445461 | 0.74 | SMN1; SMN2 (0.61) | RAB9ANPC1POLBHTTSMN1; SMN2 | |
| SCHEMBL1721544 | 0.74 | SMN1; SMN2 (0.65) | RAB9ANPC1POLBHTTSMN1; SMN2 | |
| SCHEMBL1520680 | 0.74 | RAB9A (0.77) | RAB9ANPC1POLBHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183780-A1 | Pyrazole compounds useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183780-A1 | Pyrazole compounds useful in the treatment of inflammation | ALOX15, ALOX12, ALOX15B | RAB9A 3284/4885NPC1 3112/4885POLB 2660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.