Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.63 |
| ▸ | NAMPT | P43490 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002505 | 0.82 | ALOX15 (0.62) | ALOX15NAMPTKMT2AALDH1A1USP2 | |
| SCHEMBL6004843 | 0.78 | ALOX15 (0.69) | ALOX15NAMPTKMT2AF2ALDH1A1 | |
| SCHEMBL6002607 | 0.77 | ALOX15 (0.65) | ALOX15NAMPTKMT2AALDH1A1 | |
| SCHEMBL6003810 | 0.76 | ALOX15 (0.53) | ALOX15NAMPTKMT2AALDH1A1USP2 | |
| SCHEMBL6004193 | 0.75 | ALOX15 (0.73) | ALOX15NAMPTKMT2AALDH1A1 | |
| SCHEMBL6004374 | 0.74 | ALOX15 (0.61) | ALOX15NAMPTKMT2AALDH1A1USP2 | |
| SCHEMBL6003826 | 0.73 | ALOX15 (0.67) | ALOX15NAMPTKMT2AF2ALDH1A1 | |
| SCHEMBL3915623 | 0.73 | ALOX15 (0.65) | ALOX15NAMPTKMT2AALDH1A1HSD17B10 | |
| SCHEMBL23002371 | 0.67 | SMN1; SMN2 (0.59) | ALOX15KMT2AF2ALDH1A1 | |
| SCHEMBL23002439 | 0.65 | RAB9A (0.66) | ALOX15KMT2AF2ALDH1A1S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183780-A1 | Pyrazole compounds useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-08-17 | — | — | US | disclosed |
| EP-1603897-A1 | PYRAZOLE COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004080999-A1 | PYRAZOLE COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2004-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183780-A1 | Pyrazole compounds useful in the treatment of inflammation | ALOX15, ALOX12, ALOX15B | ALOX15 1/4885NAMPT 1461/4885KMT2A 4358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.