Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6003857 | 0.87 | ALOX15 (0.69) | ALOX15KMT2ASMN1; SMN2LMNAMAPT | |
| SCHEMBL2909325 | 0.84 | ALOX15 (1.00) | ALOX15KMT2ANAMPTLMNANPC1 | |
| SCHEMBL6002607 | 0.84 | ALOX15 (0.65) | ALOX15KMT2ASMN1; SMN2NAMPTMAPT | |
| SCHEMBL6004374 | 0.83 | ALOX15 (0.61) | ALOX15KMT2ASMN1; SMN2NAMPTMAPT | |
| SCHEMBL6004843 | 0.78 | ALOX15 (0.69) | ALOX15KMT2ASMN1; SMN2NAMPTLMNA | |
| SCHEMBL6002505 | 0.77 | ALOX15 (0.62) | ALOX15KMT2ASMN1; SMN2NAMPTMAPT | |
| SCHEMBL6003798 | 0.75 | ALOX15 (0.63) | ALOX15KMT2ANAMPTALDH1A1 | |
| SCHEMBL6003826 | 0.75 | ALOX15 (0.67) | ALOX15KMT2ASMN1; SMN2NAMPTLMNA | |
| SCHEMBL3915623 | 0.75 | ALOX15 (0.65) | ALOX15KMT2ANAMPTMAPTNPC1 | |
| SCHEMBL15741795 | 0.71 | ALDH1A1 (0.66) | ALOX15KMT2ALMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183780-A1 | Pyrazole compounds useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183780-A1 | Pyrazole compounds useful in the treatment of inflammation | ALOX15, ALOX12, ALOX15B | ALOX15 1/4885KMT2A 4358/4885SMN1; SMN2 4299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.