Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.74 |
| ▸ | RAB9A | P51151 | 13/20 | 0.61 |
| ▸ | NPC1 | O15118 | 12/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.56 |
| ▸ | RELA | Q04206 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | AHR | P35869 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6004189 | 0.90 | ALOX15 (0.66) | ALOX15RAB9ANPC1PKMSMN1; SMN2 | |
| SCHEMBL6004044 | 0.90 | ALOX15 (0.74) | ALOX15RAB9ANPC1PKMSMN1; SMN2 | |
| SCHEMBL6004808 | 0.84 | ALOX15 (0.56) | ALOX15RAB9ANPC1PKMSMN1; SMN2 | |
| SCHEMBL6004187 | 0.83 | ALOX15 (0.67) | ALOX15RAB9ANPC1PKMSMN1; SMN2 | |
| SCHEMBL6003902 | 0.80 | ALOX15 (0.63) | ALOX15RAB9ANPC1PKMSMN1; SMN2 | |
| SCHEMBL6004374 | 0.80 | ALOX15 (0.61) | ALOX15RAB9ANPC1PKMSMN1; SMN2 | |
| SCHEMBL27179668 | 0.73 | RAB9A (0.90) | RAB9ANPC1PKMSMN1; SMN2MAPT | |
| SCHEMBL3430181 | 0.73 | ALDH1A1 (0.55) | RAB9ANPC1PKMSMN1; SMN2MAPT | |
| SCHEMBL13210629 | 0.73 | MAPT (0.81) | RAB9ANPC1PKMSMN1; SMN2MAPT | |
| SCHEMBL5460655 | 0.73 | RAB9A (0.69) | RAB9ANPC1PKMSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183780-A1 | Pyrazole compounds useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-08-17 | — | — | US | disclosed |
| EP-1603897-A1 | PYRAZOLE COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004080999-A1 | PYRAZOLE COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2004-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183780-A1 | Pyrazole compounds useful in the treatment of inflammation | ALOX15, ALOX12, ALOX15B | ALOX15 1/4885RAB9A 3284/4885NPC1 3112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.