Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1692394 | 0.85 | DHODH (0.44) | HTTKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL6004845 | 0.84 | MAPK14 (0.52) | KDM4EALDH1A1HPGDRIPK1KMT2A | |
| SCHEMBL6004302 | 0.84 | KDM4E (0.43) | KDM4EALDH1A1HPGDRIPK1KMT2A | |
| SCHEMBL3892242 | 0.84 | COMT (0.43) | HTTKDM4EALDH1A1HPGDRIPK1 | |
| SCHEMBL6004768 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL22824561 | 0.81 | PDE10A (0.42) | CYP1A2CYP2C19HTTKDM4EALDH1A1 | |
| SCHEMBL6004176 | 0.81 | SLC22A12 (0.41) | TRPV1 | |
| SCHEMBL6004865 | 0.78 | L3MBTL1 (0.54) | CYP1A2KDM4EALDH1A1DAONPC1 | |
| SCHEMBL30060806 | 0.76 | KDM4E (0.43) | CYP1A2CYP2C19HTTKDM4EALDH1A1 | |
| SCHEMBL10112536 | 0.74 | ALDH1A1 (0.61) | CYP1A2CYP2C19HTTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724268-A1 | COMPOUND HAVING TGF-BETA INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-11-22 | — | — | EP | disclosed |