Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | F2 | P00734 | 2/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.52 |
| ▸ | EPHB3 | P54753 | 9/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13210095 | 0.84 | RAB9A (0.60) | RAB9ANPC1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL6004813 | 0.79 | RAB9A (0.53) | RAB9ANPC1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL21883127 | 0.79 | RAB9A (0.49) | RAB9ANPC1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL6004192 | 0.79 | KMT2A (0.58) | RAB9ANPC1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL21883161 | 0.73 | KMT2A (0.51) | RAB9ANPC1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL29960964 | 0.72 | NPC1 (0.74) | RAB9ANPC1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL3794850 | 0.72 | NPC1 (0.74) | RAB9ANPC1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL23070276 | 0.71 | NPC1 (0.59) | RAB9ANPC1KMT2ASMN1; SMN2ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL20302203 | 0.70 | MCL1 (0.69) | RAB9ANPC1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL31680566 | 0.70 | CYP1A2 (0.89) | RAB9ANPC1KMT2AEPHB3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060183780-A1 | Pyrazole compounds useful in the treatment of inflammation | BIOLIPOX AB (SE) | 2006-08-17 | — | — | US | disclosed |
| EP-1603897-A1 | PYRAZOLE COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004080999-A1 | PYRAZOLE COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2004-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183780-A1 | Pyrazole compounds useful in the treatment of inflammation | ALOX15, ALOX12, ALOX15B | RAB9A 3284/4885NPC1 3112/4885KMT2A 4358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.