Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GFER | P55789 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | GUSB | P08236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746606 | 0.96 | NR3C1 (0.45) | NR3C1ALDH1A1GFERLMNAMEN1 | |
| Sulfuric Acid SCHEMBL9555432 | 0.85 | ALDH1A1 (0.50) | NR3C1ALDH1A1LMNAMEN1KMT2A | |
| Sulfuric Acid SCHEMBL9489797 | 0.85 | GFER (0.51) | ALDH1A1GFERLMNAMEN1KMT2A | |
| SCHEMBL7897227 | 0.80 | GFER (0.51) | ALDH1A1GFERLMNAMEN1KMT2A | |
| SCHEMBL6665261 | 0.78 | MTNR1A (0.52) | GFERMEN1KMT2AMAPTGAA | |
| SCHEMBL8649016 | 0.78 | GFER (0.51) | ALDH1A1GFERLMNAMEN1KMT2A | |
| SCHEMBL9854054 | 0.77 | ALDH1A1 (0.46) | NR3C1ALDH1A1GFERLMNAMEN1 | |
| Sulfuric Acid SCHEMBL6479893 | 0.76 | S100B (0.57) | ALDH1A1GFERLMNAMEN1KMT2A | |
| Sulfuric Acid SCHEMBL10900457 | 0.76 | S100B (0.57) | ALDH1A1GFERLMNAMEN1KMT2A | |
| Sulfuric Acid SCHEMBL4912919 | 0.76 | S100B (0.57) | ALDH1A1GFERLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041438-B1 | Silver halide photographic light-sensitive material, heterocyclic azo dye forming compound, and method of preparing dye | FUJI PHOTO FILM CO LTD (JP) | 2006-06-14 | — | — | EP | disclosed |
| EP-0543403-B1 | Color reversal image forming process | FUJI PHOTO FILM CO LTD (JP) | 1998-03-25 | — | — | EP | disclosed |
| EP-0567126-A1 | Processing composition for silver halide photographic material and processing method using same | FUJI PHOTO FILM CO., LTD. (JP) | 1993-10-27 | — | — | EP | disclosed |
| EP-0294149-B1 | SILVER HALIDE PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL AND PROCESSING METHOD THEREFORE | KONICA CORPORATION (JP) | 1993-09-01 | — | — | EP | disclosed |
| US-5223380-A | Using a p-phenylenediamine color developing agent | FUJI PHOTO FILM CO., LTD. (JP) | 1993-06-29 | — | — | US | disclosed |
| EP-0543403-A1 | Color reversal image forming process | FUJI PHOTO FILM CO., LTD. (JP) | 1993-05-26 | — | — | EP | disclosed |
| EP-0422513-A2 | A silver halide photographic light-sensitive material containing a novel yellow coupler | KONICA CORPORATION (JP) | 1991-04-17 | — | — | EP | disclosed |
| EP-0360289-A2 | Positive working silver halide color photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1990-03-28 | — | — | EP | disclosed |
| EP-0357082-A2 | Silver halide photographic emulsions | FUJI PHOTO FILM CO., LTD. (JP) | 1990-03-07 | — | — | EP | disclosed |
| EP-0294149-A2 | Silver halide photographic light-sensitive material and processing method therefore | KONICA CORPORATION (JP) | 1988-12-07 | — | — | EP | disclosed |