Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.44 |
| ▸ | HTR3B | O95264 | 2/20 | 0.44 |
| ▸ | HTR3A | P46098 | 2/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2291747 | 0.83 | MEN1 (0.55) | ALDH1A1HSD17B10CYP1A2TDP1HPGD | |
| SCHEMBL23257818 | 0.81 | MEN1 (0.58) | ALDH1A1HSD17B10CYP1A2TDP1HPGD | |
| SCHEMBL69928 | 0.79 | CYP1A2 (0.50) | ALDH1A1HSD17B10CYP1A2TDP1HPGD | |
| SCHEMBL7751770 | 0.79 | CYP1A2 (0.50) | ALDH1A1HSD17B10CYP1A2TDP1HPGD | |
| SCHEMBL1354442 | 0.79 | HTR3E (0.58) | ALDH1A1HSD17B10CYP1A2TDP1HTR3E | |
| SCHEMBL49212 | 0.79 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CYP1A2TDP1HPGD | |
| SCHEMBL2582570 | 0.78 | SIGMAR1 (0.49) | ALDH1A1HSD17B10CYP1A2TDP1HPGD | |
| SCHEMBL5145155 | 0.77 | RAB9A (0.51) | ALDH1A1HSD17B10CYP1A2TDP1HPGD | |
| SCHEMBL2254008 | 0.76 | SIGMAR1 (0.49) | ALDH1A1HSD17B10CYP1A2TDP1HPGD | |
| SCHEMBL6541655 | 0.74 | HPRT1 (0.61) | ALDH1A1HSD17B10CYP1A2TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1734792-A | Molecular photovoltaics, method of manufacture and articles derived therefrom | GEN ELECTRIC (US) | 2006-02-15 | — | — | CN | claimed |
| CN-100570923-C | OLED lamp and manufacture method thereof | EASTMAN KODAK CO (US) | 2009-12-16 | — | — | CN | disclosed |
| CN-1734792-A | Molecular photovoltaics, method of manufacture and articles derived therefrom | GEN ELECTRIC (US) | 2006-02-15 | — | — | CN | disclosed |
| EP-1207161-B1 | NOVEL ISOINDOLE DERIVATIVES | BANYU PHARMA CO LTD (JP) | 2006-01-18 | — | — | EP | disclosed |
| US-6777410-B2 | SUCH AS 9-(2-METHOXYPHENYL)-3-(1-METHYLETHYL)-(1,3)OXAZOLO-(2,3)ISOINDOLE-2,5(3H,9H)-DIONE; DIABETES AND COMPLICATIONS; OBESITY | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2004-08-17 | — | — | US | disclosed |
| CN-1497750-A | OLED lamp | ��˹���´﹫˾ | 2004-05-19 | — | — | CN | disclosed |
| CN-1498050-A | High-power function metal alloy cathode used in organic electroluminescence device | ��˹���´﹫˾ | 2004-05-19 | — | — | CN | disclosed |
| US-20040053923-A1 | Novel isoindole derivatives | BANYU PHARMACEUTICAL CO., LTD. | 2004-03-18 | — | — | US | disclosed |
| US-6608098-B1 | Diabetes or obesity, 2-(4-(3-isopropyl-2,5-dioxo-2,3-dihydro-1H-pyrrolo(2,1-a) isoindol-9(5H)-yl)phenoxy)-N-propylacetamide | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2003-08-19 | — | — | US | disclosed |
| EP-1207161-A1 | NOVEL ISOINDOLE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2002-05-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053923-A1 | Novel isoindole derivatives | GPR119, SLC5A2, SLC5A1 | ALDH1A1 228/4885HSD17B10 418/4885CYP1A2 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.