Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6007699 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2SLC6A3SIGMAR1ACHECCR3 | |
| SCHEMBL9179426 | 0.87 | OPRM1 (0.46) | SIGMAR1 | |
| SCHEMBL7497626 | 0.76 | SMN1; SMN2 (0.41) | SMN1; SMN2SLC6A3SIGMAR1ACHECCR3 | |
| SCHEMBL9187010 | 0.75 | OPRM1 (0.54) | SIGMAR1 | |
| SCHEMBL11461429 | 0.75 | SLC6A3 (0.45) | SLC6A3SIGMAR1ACHEKCNH2DRD2 | |
| SCHEMBL7510207 | 0.73 | SLC6A3 (0.44) | SLC6A3SIGMAR1ACHECCR3DRD2 | |
| Hydrochloric Acid SCHEMBL11087688 | 0.73 | SLC6A3 (0.44) | SLC6A3SIGMAR1ACHEKCNH2DRD2 | |
| SCHEMBL6007978 | 0.72 | GRM2 (0.47) | SLC6A3SIGMAR1ACHEKCNH2 | |
| SCHEMBL6007973 | 0.72 | GRM2 (0.47) | SLC6A3SIGMAR1ACHEKCNH2 | |
| SCHEMBL8924879 | 0.70 | OPRM1 (0.41) | SIGMAR1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0924213-B1 | PYRIDOBENZOXAZINE DERIVATIVES | DAIICHI SEIYAKU CO (JP) | 2006-06-28 | — | — | EP | disclosed |
| EP-0807630-B1 | HETEROCYCLIC COMPOUNDS | DAIICHI SEIYAKU CO (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-1304329-A2 | Pyridonecarboxylic acid derivatives and their use as antibacterial agents | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6191129-B1 | MICROBIOCIDES, BACTERICIDES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-02-20 | — | — | US | disclosed |
| EP-0924213-A1 | PYRIDOBENZOXAZINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1999-06-23 | — | — | EP | disclosed |
| EP-0807630-A1 | HETEROCYCLIC COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | disclosed |