SCHEMBL6008423

SCHEMBL6008423

CC(C)(C)[Si](C)(C)ON1CCCC1=O

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.39
BRD2 P25440 1/20 0.39
PIK3CD O00329 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL366269 0.82 BRD4 (0.43) BRD4BRD2PIK3CDL3MBTL1
SCHEMBL20531775 0.74 PREP (0.33)
SCHEMBL30786361 0.73 BCAT2 (0.37)
SCHEMBL6449914 0.72 PIK3CD (0.43) PIK3CD
SCHEMBL15161544 0.71 BRD4 (0.44) BRD4BRD2PIK3CDL3MBTL1
SCHEMBL5962649 0.70
SCHEMBL21389245 0.69 KMT2A (0.42) BRD4BRD2PIK3CD
SCHEMBL2930849 0.69 BRD4 (0.46) BRD4BRD2PIK3CD
SCHEMBL6122067 0.69 BRD4 (0.46) BRD4BRD2PIK3CD
SCHEMBL6199346 0.69 GRM5 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11912692-B2 Substituted S-alaninate derivatives BAYER AKTIENGESELLSCHAFT (DE) 2024-02-27 US disclosed
CN-117043164-A Imidazopyridazine or pyrazolopyrimidine compounds and compositions 安锐生物医药科技(广州)有限公司 2023-11-10 CN disclosed
EP-3154976-A2 PURINE INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA Merck Sharp & Dohme Corp. (US) 2017-04-19 EP disclosed
US-20060040918-A1 Benzo d!azepine derivatives for the treatment of neurological disorders GLAXO GROUP LIMITED (GB) 2006-02-23 US disclosed
EP-1048669-A1 CARBAPENEM DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 2000-11-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11912692-B2 Substituted S-alaninate derivatives AAAS, ALAD, AASDHPPT BRD4 4805/4885BRD2 4803/4885PIK3CD 2257/4885
US-20060040918-A1 Benzo d!azepine derivatives for the treatment of neurological disorders DRD1, DRD2, DRD3 BRD4 265/4885BRD2 242/4885PIK3CD 3904/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.