Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6009061 | 0.92 | PTGS2 (0.56) | ALDH1A1CYP3A4MAPK1PTGS2PTGS1 | |
| SCHEMBL13731761 | 0.92 | PTGS2 (0.56) | ALDH1A1CYP3A4MAPK1PTGS2PTGS1 | |
| SCHEMBL13731763 | 0.91 | ALDH1A1 (0.55) | ALDH1A1CYP3A4MAPK1PTGS2PTGS1 | |
| SCHEMBL11045136 | 0.83 | PTGS2 (0.53) | ALDH1A1MAPK1PTGS2PTGS1HTT | |
| SCHEMBL10459473 | 0.82 | ALDH1A1 (0.46) | ALDH1A1CYP3A4MAPK1PTGS2PTGS1 | |
| SCHEMBL5890635 | 0.81 | ALDH1A1 (0.50) | ALDH1A1PTGS2PTGS1 | |
| SCHEMBL3006195 | 0.78 | ALDH1A1 (0.73) | ALDH1A1CYP3A4MAPK1GAAHTT | |
| SCHEMBL250144 | 0.78 | ALDH1A1 (0.80) | ALDH1A1CYP3A4MAPK1GAAHTT | |
| SCHEMBL9766560 | 0.78 | TSHR (0.50) | ALDH1A1PTGS2KMT2AMEN1THRB | |
| SCHEMBL2311184 | 0.78 | LRRK2 (0.56) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791094-B1 | A PROCESS FOR MANUFACTURING HALOARYL COMPOUNDS FROM MIXTURES OF ISOMERS OF DIHALODIARYLSULFONES | SOLVAY SPECIALTY POLYMERS USA (US) | 2021-02-17 | — | — | EP | disclosed |
| EP-2699541-B1 | PROCESS FOR THE MANUFACTURE OF DIHALODIPHENYLSULFONES STARTING FROM ORGANIC ACIDS | SOLVAY SPECIALTY POLYMERS USA (US) | 2017-06-14 | — | — | EP | disclosed |
| US-9388128-B2 | Process for the manufacture of dihalodiphenylsulfones starting from organic acids | SOLVAY SPECIALITY POLYMERS USA, LLC (US) | 2016-07-12 | — | — | US | disclosed |
| US-9212111-B2 | Process for manufacturing haloaryl compounds from mixtures of isomers of dihalodiarylsulfone | SOLVAY SPECIALTY POLYMERS USA, LLC (US) | 2015-12-15 | — | — | US | disclosed |
| US-20140323765-A1 | Process for Manufacturing Haloaryl Compounds From Mixtures of Isomers of Dihalodiarylsulfone | SOLVAY SPECIALTY POLYMERS USA, LLC. (US) | 2014-10-30 | — | — | US | disclosed |
| EP-2791094-A1 | A PROCESS FOR MANUFACTURING HALOARYL COMPOUNDS FROM MIXTURES OF ISOMERS OF DIHALODIARYLSULFONES | Solvay Specialty Polymers USA, LLC. (US) | 2014-10-22 | — | — | EP | disclosed |
| US-20140228597-A1 | Process for the manufacture of dihalodiphenylsulfones starting from organic acids | SOLVAY SPECIALITY POLYMERS USA, LLC (US) | 2014-08-14 | — | — | US | disclosed |
| EP-2699541-A1 | PROCESS FOR THE MANUFACTURE OF DIHALODIPHENYLSULFONES STARTING FROM ORGANIC ACIDS | Solvay Specialty Polymers USA, LLC. (US) | 2014-02-26 | — | — | EP | disclosed |
| WO-2013087594-A1 | A PROCESS FOR MANUFACTURING HALOARYL COMPOUNDS FROM MIXTURES OF ISOMERS OF DIHALODIARYLSULFONES | SOLVAY SPECIALTY POLYMERS USA, LLC (US) | 2013-06-20 | — | — | WO | disclosed |
| WO-2012143279-A1 | PROCESS FOR THE MANUFACTURE OF DIHALODIPHENYLSULFONES STARTING FROM ORGANIC ACIDS | SOLVAY SPECIALTY POLYMERS USA, LLC (US) | 2012-10-26 | — | — | WO | disclosed |
| EP-1112301-B1 | ION-EXCHANGE POLYMERS | VICTREX MFG LTD (GB) | 2006-09-06 | — | — | EP | disclosed |
| US-6969755-B2 | polyether ketone and/or sulfone copolymers having chemical resistance, used as polyelectrolyte membranes for fuel cells | VICTREX MANUFACTURING LIMITED (GB) | 2005-11-29 | — | — | US | disclosed |
| EP-1493770-A2 | Ion-exchange polymers | VICTREX MANUFACTURING LIMITED (GB) | 2005-01-05 | — | — | EP | disclosed |
| US-6828353-B1 | Sulphonated polyaryletherketones, polyarylethersulphones and/or copolymers of | VICTREX MANUFACTURING LIMITED (GB) | 2004-12-07 | — | — | US | disclosed |
| US-20040242710-A1 | Ion-exchange polymers | VICTREX MANUFACTURING LIMITED (GB) | 2004-12-02 | — | — | US | disclosed |
| EP-0278720-B1 | Aromatic polymer | VICTREX MFG LTD (GB) | 1995-01-18 | — | — | EP | disclosed |
| US-5116933-A | Crystalline | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140323765-A1 | Process for Manufacturing Haloaryl Compounds From Mixtures of Isomers of Dihalodiarylsulfone | HDHD5, DHCR7, DDT | ALDH1A1 303/4885CYP3A4 61/4885MAPK1 2512/4885 |
| US-20140228597-A1 | Process for the manufacture of dihalodiphenylsulfones starting from organic acids | DDT, CYP2B6, HPD | ALDH1A1 669/4885CYP3A4 8/4885MAPK1 2513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.