Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | LOX | P28300 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6009061 | 0.88 | PTGS2 (0.56) | PTGS2MAPTSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL13731761 | 0.88 | PTGS2 (0.56) | PTGS2MAPTSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL29639004 | 0.88 | PTGS2 (0.56) | PTGS2MAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL27859837 | 0.86 | PTGS2 (0.53) | PTGS2HTR6MAOALOXCA12 | |
| SCHEMBL6009067 | 0.83 | ALDH1A1 (0.48) | PTGS2HTR6MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5305256 | 0.83 | TSHR (0.52) | PTGS2SMN1; SMN2ALDH1A1POLBMEN1 | |
| SCHEMBL4733933 | 0.83 | CA2 (0.61) | PTGS2CA12CA1CA2CA9 | |
| SCHEMBL18424825 | 0.83 | ALDH1A1 (0.52) | PTGS2CA12CA1CA2CA9 | |
| SCHEMBL5524387 | 0.82 | VCAM1 (0.46) | PTGS2HTR6MAOALOXPTGS1 | |
| SCHEMBL9713722 | 0.82 | BACE1 (0.56) | PTGS2HTR6MAOALOXCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4543416-A | Di(phthalic anhydride) derivatives of di(disubstituted phenol) sulfones | GENERAL ELECTRIC COMPANY (US) | 1985-09-24 | — | — | US | disclosed |
| US-4523006-A | Polyetherimides of di(phthalic anhydride) derivatives of di(substituted phenol) sulfones | GENERAL ELECTRIC COMPANY (US) | 1985-06-11 | — | — | US | disclosed |
| EP-0117416-A1 | Novel monomers and polyetherimides prepared therefrom | GENERAL ELECTRIC COMPANY (US) | 1984-09-05 | — | — | EP | disclosed |