SCHEMBL6010404

SCHEMBL6010404

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nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.39
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 1/20 0.37
DUSP3 P51452 1/20 0.37
LMNA P02545 1/20 0.37
FPR2 P25090 2/20 0.35
ATM Q13315 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
CA2 P00918 3/20 0.33
CA1 P00915 2/20 0.33
DPP4 P27487 1/20 0.33
DGKA P23743 1/20 0.33
MME P08473 1/20 0.33
ACE P12821 1/20 0.33
CPA1 P15085 1/20 0.33
ACE2 Q9BYF1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6010216 0.85 KDM4E (0.37) MEN1KMT2AKDM4EDUSP3LMNA
SCHEMBL6010265 0.78 KDM4E (0.35) ALDH1A1MEN1KMT2AKDM4EDUSP3
SCHEMBL6010401 0.76 ALDH1A1 (0.49) ALDH1A1L3MBTL1MEN1KMT2AFPR2
SCHEMBL6010410 0.76 ALDH1A1 (0.49) ALDH1A1L3MBTL1MEN1KMT2AFPR2
SCHEMBL8851847 0.75 ALDH1A1 (0.39) ALDH1A1L3MBTL1MEN1KMT2AKDM4E
SCHEMBL28746812 0.73 ALDH1A1 (0.46) ALDH1A1L3MBTL1MEN1KMT2AFPR2
SCHEMBL27831338 0.73 ALDH1A1 (0.53) ALDH1A1L3MBTL1MEN1KMT2AFPR2
SCHEMBL6010366 0.72 ALDH1A1 (0.44) ALDH1A1MEN1KMT2ALMNAMME
SCHEMBL6009834 0.72 TGFBR1 (0.40) ALDH1A1MEN1KMT2AKDM4EDUSP3
SCHEMBL9405945 0.70 LMNA (0.36) ALDH1A1MEN1KMT2AKDM4EDUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060018864-A1 Cosmetic preparation containing glycerylamino acid derivative SEIWA KASEI COMPANY, LIMITED (JP) 2006-01-26 US disclosed
EP-1584320-A1 COSMETIC PREPARATION CONTAINING GLYCERYLAMINO ACID DERIVATIVE Seiwa Kasei Company, Limited (JP) 2005-10-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060018864-A1 Cosmetic preparation containing glycerylamino acid derivative GLA, GPKOW, CUTA ALDH1A1 819/4885L3MBTL1 3939/4885MEN1 2277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.