Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 8/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 3/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6487554 | 0.81 | PTGES (0.51) | PTGESHRH4 | |
| SCHEMBL3081079 | 0.81 | HTR6 (0.49) | GPR119NCF1HTR6 | |
| SCHEMBL6010877 | 0.80 | NCF1 (0.40) | NCF1HTR6CHRNB2CHRNA4SOS1 | |
| SCHEMBL3088134 | 0.80 | SOS1 (0.56) | PTGESGPR119HTR6CHRNB2CHRNA4 | |
| SCHEMBL3082150 | 0.80 | PTGES (0.53) | PTGESHTR6HRH4 | |
| SCHEMBL6500082 | 0.79 | HTR6 (0.42) | GPR119HTR6HRH4 | |
| SCHEMBL6010826 | 0.79 | NCF1 (0.39) | NCF1HTR6CHRNB2CHRNA4SOS1 | |
| SCHEMBL4158366 | 0.78 | CHRNB2 (0.42) | NCF1HTR6CHRNB2CHRNA4SOS1 | |
| SCHEMBL6489251 | 0.77 | LMNA (0.52) | PTGESGPR119HTR6 | |
| Hydrochloric Acid SCHEMBL6010728 | 0.77 | CHRNB2 (0.41) | NCF1HTR6CHRNB2CHRNA4SOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1134220-A1 | BENZOXAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | claimed |
| US-7045516-B1 | Benzoxazole derivatives and drugs containing the same as the active ingredient | KOICHI SHUDO (JP) | 2006-05-16 | — | — | US | disclosed |
| EP-1134220-B1 | BENZOXAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | SHUDO KOICHI (JP) | 2004-08-18 | — | — | EP | disclosed |
| EP-1134220-A1 | BENZOXAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |