Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2236097 | 0.89 | HDAC1 (0.37) | ALDH1A1SMN1; SMN2RAB9ANPC1CYP1A2 | |
| SCHEMBL17923455 | 0.85 | MAPT (0.37) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL17923449 | 0.85 | SMN1; SMN2 (0.36) | ALDH1A1SMN1; SMN2NPC1MAPTMEN1 | |
| SCHEMBL17923453 | 0.85 | MAPT (0.35) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL3892309 | 0.80 | NPC1 (0.37) | SMN1; SMN2RAB9ANPC1CYP3A4MAPT | |
| SCHEMBL6011885 | 0.76 | NCOA3 (0.31) | ALDH1A1CYP3A4HPGDMAPT | |
| SCHEMBL14000174 | 0.76 | MAPT (0.38) | ALDH1A1RAB9ANPC1HPGDMAPT | |
| SCHEMBL2238014 | 0.75 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2RAB9ANPC1CYP1A2 | |
| SCHEMBL2237688 | 0.75 | HDAC1 (0.39) | SMN1; SMN2CYP2C19MAPTMEN1KMT2A | |
| SCHEMBL3557373 | 0.75 | MAPT (0.36) | ALDH1A1SMN1; SMN2RAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020038812-A1 | NEW PROCESS FOR THE PREPARATION OF AMENAMEVIR | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-02-27 | — | — | WO | disclosed |
| EP-1652843-A1 | AMIDE DERIVATIVES | Astellas Pharma Inc. (JP) | 2006-05-03 | — | — | EP | disclosed |