Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21769740 | 0.94 | L3MBTL1 (0.33) | MAPTALDH1A1KMT2AMEN1TP53 | |
| SCHEMBL21769573 | 0.91 | POLB (0.39) | MAPTALDH1A1KMT2AMEN1TP53 | |
| SCHEMBL21769854 | 0.90 | KMT2A (0.39) | MAPTALDH1A1KMT2AMEN1THRB | |
| SCHEMBL2237823 | 0.90 | HDAC1 (0.39) | MAPTALDH1A1KMT2AMEN1TP53 | |
| SCHEMBL17923449 | 0.89 | SMN1; SMN2 (0.36) | MAPTALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL17923455 | 0.88 | MAPT (0.37) | MAPTALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL21769571 | 0.88 | SLC6A9 (0.36) | MAPT | |
| SCHEMBL21769874 | 0.88 | MAPT (0.38) | MAPTALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL21769731 | 0.87 | KMT2A (0.40) | MAPTALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL21769885 | 0.86 | POLB (0.37) | MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2263671-B1 | AMIDE DERIVATIVE-CONTAINING PHARMACEUTICAL COMPOSITION | ASTELLAS PHARMA INC (JP) | 2016-07-20 | — | — | EP | claimed |
| WO-2020038812-A1 | NEW PROCESS FOR THE PREPARATION OF AMENAMEVIR | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-02-27 | — | — | WO | disclosed |