Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.30 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2241378 | 0.90 | HDAC1 (0.36) | IDO1ALDH1A1ABL1 | |
| SCHEMBL21769574 | 0.89 | HCRTR1 (0.31) | HCRTR1HCRTR2CYP3A4 | |
| SCHEMBL21769850 | 0.87 | HCRTR1 (0.35) | ALDH1A1GAAMAPTHPGDSLC6A9 | |
| SCHEMBL21769853 | 0.87 | POLB (0.38) | ALDH1A1GAAMAPTHPGD | |
| SCHEMBL21769566 | 0.87 | KMT2A (0.37) | ADORA2AADORA1ALDH1A1GAAMAPT | |
| SCHEMBL21769571 | 0.86 | SLC6A9 (0.36) | NCOA3IDO1MAPTSLC6A9 | |
| SCHEMBL17923453 | 0.85 | MAPT (0.35) | ALDH1A1MAPT | |
| SCHEMBL21769885 | 0.84 | POLB (0.37) | ADORA2AADORA1ALDH1A1GAAMAPT | |
| SCHEMBL3892309 | 0.84 | NPC1 (0.37) | NCOA3ADORA2AADORA1MAPTGPR119 | |
| SCHEMBL21769740 | 0.84 | L3MBTL1 (0.33) | ALDH1A1GAAMAPTSLC6A9HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1652843-A1 | AMIDE DERIVATIVES | Astellas Pharma Inc. (JP) | 2006-05-03 | — | — | EP | claimed |