Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28005325 | 0.86 | ADORA2A (0.36) | NPC1RAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL1539828 | 0.83 | CYP3A4 (0.41) | NPC1RAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL4246291 | 0.83 | KMT2A (0.40) | NPC1RAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL27913794 | 0.81 | KMT2A (0.41) | NPC1RAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL1414517 | 0.80 | GUSB (0.35) | NPC1RAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL28037210 | 0.80 | EPRS1 (0.39) | NPC1RAB9AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27792351 | 0.72 | BCAT2 (0.39) | NPC1RAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL31620950 | 0.72 | ACHE (0.52) | NPC1RAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL28191136 | 0.72 | ACHE (0.52) | NPC1RAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL5851572 | 0.72 | ACHE (0.52) | NPC1RAB9AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1063264-B1 | Reaction product, process of producing same, electrophotographic photoconductor using same, electrophotographic apparatus having the photoconductor, and process cartridge for electrophotographic apparatus | RICOH KK (JP) | 2006-03-01 | — | — | EP | disclosed |
| US-20030013028-A1 | Reaction product, process for the production thereof, electrophotographic photoconductor using the reaction product, electrophotographic apparatus using the photoconductor, and process cartridge for electrophotographic apparatus | RICOH COMPANY, LTD. (JP) | 2003-01-16 | — | — | US | disclosed |
| US-6465648-B1 | OBTAINABLE BY REACTING (I) A NITRILE DERIVATIVE, (II) A PHTHALONITRILE DERIVATIVE OR A 1,3-DIIMINOISOINDOLINE DERIVATIVE AND, IF NECESSARY, (III) A METAL OR A METAL-CONTAINING COMPOUND, SUCH AS TITANIUM. | RICOH COMPANY, LTD. (JP) | 2002-10-15 | — | — | US | disclosed |
| EP-1063264-A2 | Reaction product, process of producing same, electrophotographic photoconductor using same, electrophotographic apparatus having the photoconductor, and process cartridge for electrophotographic apparatus | Ricoh Company, Ltd. (JP) | 2000-12-27 | — | — | EP | disclosed |