Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3451041 | 1.00 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1CALCRLFPR2 | |
| SCHEMBL6015050 | 0.92 | YAP1 (0.45) | CALCRL | |
| SCHEMBL6015116 | 0.91 | CYP51A1 (0.42) | ALDH1A1KMT2AMEN1CALCRLFPR2 | |
| SCHEMBL6015142 | 0.90 | FPR2 (0.42) | CALCRLFPR2CYP3A4 | |
| SCHEMBL6015112 | 0.88 | CCR1 (0.38) | FPR2KDM4E | |
| SCHEMBL3449290 | 0.87 | FPR2 (0.49) | FPR2CYP51A1CHRM1 | |
| SCHEMBL3448805 | 0.87 | FPR2 (0.49) | FPR2CYP51A1CHRM1 | |
| SCHEMBL3449020 | 0.87 | FPR2 (0.49) | FPR2CYP51A1CHRM1 | |
| SCHEMBL6015073 | 0.86 | CCR1 (0.40) | — | |
| SCHEMBL6015029 | 0.86 | CCR1 (0.40) | ALDH1A1KMT2AMEN1CALCRLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1695961-A1 | UREA DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2006-08-30 | — | — | EP | disclosed |