Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.50 |
| ▸ | DCPS | Q96C86 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 3/20 | 0.39 |
| ▸ | CYBB | P04839 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015551 | 0.77 | DCPS (0.49) | KDM4EALDH1A1HPGDDCPSSMN1; SMN2 | |
| SCHEMBL6015536 | 0.76 | KCNH2 (0.39) | KDM4EALDH1A1HPGDDCPSL3MBTL1 | |
| SCHEMBL6015868 | 0.75 | DCPS (0.46) | DCPSDHFR | |
| SCHEMBL6015553 | 0.74 | DCPS (0.43) | KDM4EALDH1A1HPGDDCPSL3MBTL1 | |
| SCHEMBL6015544 | 0.71 | DCPS (0.57) | DCPSDHFR | |
| SCHEMBL25959237 | 0.70 | TLR7 (0.42) | KDM4EALDH1A1HPGDMTNR1AMTNR1B | |
| SCHEMBL6015540 | 0.70 | DCPS (0.47) | DCPSDHFR | |
| SCHEMBL21712415 | 0.69 | TLR7 (0.53) | KDM4EALDH1A1HPGDMTNR1A | |
| SCHEMBL30662177 | 0.69 | TLR7 (0.53) | KDM4EALDH1A1HPGDMTNR1A | |
| SCHEMBL3453971 | 0.69 | KDM4E (0.64) | KDM4EALDH1A1HPGDMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054526-A2 | CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES | ELCELYX THERAPEUTICS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |