Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCPS | Q96C86 | 10/20 | 0.43 |
| ▸ | DHFR | P00374 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12322041 | 0.82 | HTR1A (0.34) | DCPSDHFRKDM4EALDH1A1HPGD | |
| SCHEMBL6015536 | 0.78 | KCNH2 (0.39) | DCPSDHFRKDM4EUSP2ALDH1A1 | |
| SCHEMBL619858 | 0.75 | SSTR4 (0.36) | KDM4EHTR1ADRD4KCNH2POLB | |
| SCHEMBL6015550 | 0.74 | KDM4E (0.53) | DCPSDHFRKDM4EALDH1A1HPGD | |
| SCHEMBL6015551 | 0.71 | DCPS (0.49) | DCPSDHFRKDM4EALDH1A1GLA | |
| SCHEMBL619066 | 0.69 | BRAF (0.34) | KDM4EALDH1A1LMNAGAAHSD17B10 | |
| SCHEMBL6015868 | 0.68 | DCPS (0.46) | DCPSDHFRKCNH2 | |
| SCHEMBL26343577 | 0.65 | HTR1A (0.39) | ALDH1A1L3MBTL1HTR1ADRD4KCNH2 | |
| SCHEMBL6015544 | 0.65 | DCPS (0.57) | DCPSDHFRCYP2D6 | |
| SCHEMBL6015543 | 0.64 | DCPS (0.80) | DCPSDHFRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054526-A2 | CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES | ELCELYX THERAPEUTICS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |