Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCPS | Q96C86 | 8/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015868 | 0.81 | DCPS (0.46) | DCPSDHFRKCNH2 | |
| SCHEMBL6015550 | 0.77 | KDM4E (0.53) | DCPSKDM4EALDH1A1HPGDDHFR | |
| SCHEMBL13982641 | 0.76 | KDM4E (0.44) | KDM4EALDH1A1HPGDCASP1HSD17B10 | |
| SCHEMBL6015544 | 0.74 | DCPS (0.57) | DCPSDHFR | |
| SCHEMBL6015543 | 0.73 | DCPS (0.80) | DCPSDHFR | |
| SCHEMBL6015541 | 0.73 | DCPS (0.59) | DCPSDHFR | |
| SCHEMBL6015536 | 0.72 | KCNH2 (0.39) | DCPSKDM4EALDH1A1HPGDCASP1 | |
| SCHEMBL9042257 | 0.72 | ACHE (0.64) | KDM4EALDH1A1HSD17B10KCNH2 | |
| SCHEMBL6015547 | 0.71 | CHRNB2 (0.51) | DCPSDHFR | |
| SCHEMBL9040699 | 0.71 | ACHE (0.62) | KDM4EALDH1A1HSD17B10KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054526-A2 | CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES | ELCELYX THERAPEUTICS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |