Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL3 | P20749 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015719 | 0.90 | POLR1A (0.46) | BCL3ALDH1A1 | |
| SCHEMBL6015658 | 0.88 | CYP1A2 (0.47) | MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL6015695 | 0.81 | DRD2 (0.47) | KMT2AALDH1A1GAA | |
| SCHEMBL6015767 | 0.76 | POLB (0.60) | HPGDALDH1A1CD274 | |
| SCHEMBL31298077 | 0.75 | KMT2A (0.67) | BCL3MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL31518356 | 0.75 | KMT2A (0.63) | BCL3MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL5795351 | 0.75 | KMT2A (0.63) | BCL3MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL28602004 | 0.75 | POLB (0.60) | BCL3MEN1KMT2A | |
| SCHEMBL8722300 | 0.75 | MEN1 (0.60) | BCL3MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL6015846 | 0.74 | MAPK1 (0.50) | MEN1KMT2AHPGDALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | claimed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |