Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | AGER | Q15109 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PER2 | O15055 | 2/20 | 0.38 |
| ▸ | CRY1 | Q16526 | 2/20 | 0.38 |
| ▸ | CRY2 | Q49AN0 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MYLK | Q15746 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 2/20 | 0.37 |
| ▸ | DNM2 | P50570 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6227403 | 0.76 | L3MBTL1 (0.34) | SMN1; SMN2TSHRALDH1A1POLBHSD17B10 | |
| SCHEMBL17956205 | 0.73 | HTR2C (0.51) | ALDH1A1POLB | |
| SCHEMBL6015764 | 0.71 | PRKCA (0.42) | MAPTSMN1; SMN2TSHRALDH1A1MEN1 | |
| SCHEMBL11171140 | 0.70 | TSHR (0.39) | MAPTSMN1; SMN2TSHRALDH1A1POLB | |
| SCHEMBL9581979 | 0.70 | — | — | |
| SCHEMBL5497340 | 0.70 | ALDH1A1 (0.34) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL17956270 | 0.70 | CDK4 (0.33) | — | |
| SCHEMBL6236614 | 0.67 | SLC9A1 (0.37) | MAPTTSHRALDH1A1MEN1KMT2A | |
| SCHEMBL6015862 | 0.67 | KMT2A (0.65) | DNM1MAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL2948314 | 0.66 | KDM4E (0.38) | MAPTSMN1; SMN2TSHRALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | claimed |
| CN-1636005-A | Benzothiazinone and benzoxazinone compounds | KNOLL AG (DE) | 2005-07-06 | — | — | CN | claimed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |
| CN-1636005-A | Benzothiazinone and benzoxazinone compounds | KNOLL AG (DE) | 2005-07-06 | — | — | CN | disclosed |