Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.46 |
| ▸ | CHKA | P35790 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 0.45 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.45 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.45 |
| ▸ | GHSR | Q92847 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015833 | 0.95 | KMT2A (0.52) | POLBKMT2AMEN1HPGDTSHR | |
| SCHEMBL6015819 | 0.81 | ALDH1A1 (0.48) | POLBKMT2AMEN1HPGDHRH4 | |
| SCHEMBL6015913 | 0.81 | SIGMAR1 (0.49) | HPGDHRH4TLR9TLR8TLR7 | |
| SCHEMBL6015694 | 0.81 | ALDH1A1 (0.49) | POLBHPGDTSHRTLR9TLR8 | |
| SCHEMBL6015723 | 0.80 | PARP1 (0.48) | — | |
| SCHEMBL6015766 | 0.80 | ALDH1A1 (0.43) | KMT2AMEN1HPGDCHKAALOX15 | |
| SCHEMBL6015942 | 0.76 | L3MBTL3 (0.61) | KMT2AMEN1 | |
| SCHEMBL6015825 | 0.75 | SPIN1 (0.48) | — | |
| SCHEMBL6015704 | 0.75 | PDE3B (0.51) | POLBKMT2AMEN1HPGDTSHR | |
| SCHEMBL6015752 | 0.74 | KMT2A (0.55) | POLBKMT2AHPGDHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | claimed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |