Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 7/20 | 0.42 |
| ▸ | MBTD1 | Q05BQ5 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.40 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015942 | 0.83 | L3MBTL3 (0.61) | ALDH1A1KDM4EL3MBTL3MBTD1L3MBTL1 | |
| SCHEMBL6015967 | 0.78 | L3MBTL3 (0.50) | ALDH1A1L3MBTL3MBTD1L3MBTL1MEN1 | |
| SCHEMBL6015766 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MAPTHSD17B10KDM4EHPGD | |
| SCHEMBL1461431 | 0.74 | HRH3 (0.55) | ALDH1A1MAPTHSD17B10KDM4EHPGD | |
| SCHEMBL6015762 | 0.73 | HTR3A (0.41) | ALDH1A1MAPTHSD17B10KDM4EHPGD | |
| SCHEMBL6015753 | 0.72 | PDE3B (0.58) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL6015678 | 0.70 | HTR3A (0.56) | ALDH1A1MAPTHSD17B10KDM4EHPGD | |
| SCHEMBL1461819 | 0.69 | ALDH1A1 (0.58) | ALDH1A1MAPTHSD17B10KDM4EHPGD | |
| SCHEMBL6015931 | 0.68 | KMT2A (0.54) | ALDH1A1KDM4EHPGDL3MBTL1MEN1 | |
| SCHEMBL11968885 | 0.68 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4EHPGDL3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | claimed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | disclosed |