Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 7/20 | 0.50 |
| ▸ | MBTD1 | Q05BQ5 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.47 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015798 | 0.78 | ALDH1A1 (0.56) | L3MBTL3MBTD1L3MBTL1TP53BP1ALDH1A1 | |
| SCHEMBL6015818 | 0.77 | LMNA (0.46) | ALDH1A1PARP1 | |
| SCHEMBL6015822 | 0.75 | CHKA (0.55) | ALDH1A1PARP1 | |
| SCHEMBL6015942 | 0.74 | L3MBTL3 (0.61) | L3MBTL3MBTD1L3MBTL1TP53BP1ALDH1A1 | |
| SCHEMBL16054572 | 0.72 | L3MBTL3 (0.58) | L3MBTL3MBTD1L3MBTL1TP53BP1TSHR | |
| SCHEMBL6554484 | 0.71 | PARP1 (0.66) | L3MBTL3MBTD1L3MBTL1TP53BP1PARP1 | |
| SCHEMBL22940166 | 0.70 | L3MBTL1 (0.63) | L3MBTL3MBTD1L3MBTL1TP53BP1TSHR | |
| SCHEMBL20640316 | 0.70 | ALDH1A1 (0.69) | L3MBTL3MBTD1L3MBTL1TP53BP1TSHR | |
| SCHEMBL13222431 | 0.70 | L3MBTL3 (0.63) | L3MBTL3MBTD1L3MBTL1TP53BP1TSHR | |
| Hydrochloric Acid SCHEMBL6404360 | 0.70 | PARP1 (0.65) | L3MBTL3MBTD1L3MBTL1TP53BP1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | claimed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |