Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015776 | 1.00 | ALDH1A1 (0.47) | ALDH1A1MAPTGAARAB9ANPC1 | |
| SCHEMBL6015876 | 0.77 | RAB9A (0.49) | ALDH1A1MAPTGAARAB9ANPC1 | |
| SCHEMBL6015883 | 0.77 | RAB9A (0.49) | ALDH1A1MAPTGAARAB9ANPC1 | |
| SCHEMBL6015616 | 0.76 | KDM4E (0.48) | ALDH1A1MAPTGAARAB9ANPC1 | |
| SCHEMBL6015615 | 0.76 | KDM4E (0.48) | ALDH1A1MAPTGAARAB9ANPC1 | |
| SCHEMBL28850677 | 0.71 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL10817027 | 0.69 | PIM1 (0.67) | ALDH1A1MAPTGAARAB9ANPC1 | |
| SCHEMBL10817032 | 0.69 | PIM1 (0.67) | ALDH1A1MAPTGAARAB9ANPC1 | |
| SCHEMBL8085252 | 0.68 | PIM1 (0.67) | ALDH1A1MAPTGAARAB9ANPC1 | |
| SCHEMBL8085249 | 0.68 | PIM1 (0.67) | ALDH1A1MAPTGAARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | disclosed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | disclosed |