Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BAP1 | Q92560 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4195517 | 0.84 | DPP4 (0.40) | NPC1RAB9AMEN1KMT2ADPP4 | |
| SCHEMBL4199975 | 0.84 | NPC1 (0.40) | ALDH1A1USP2NPC1RAB9AMEN1 | |
| SCHEMBL4197211 | 0.81 | SCN4A (0.38) | ALDH1A1USP2NPC1RAB9AMEN1 | |
| SCHEMBL4197998 | 0.81 | NPC1 (0.53) | ALDH1A1USP2NPC1RAB9AMEN1 | |
| SCHEMBL4198007 | 0.81 | RAB9A (0.42) | ALDH1A1USP2NPC1RAB9AMEN1 | |
| SCHEMBL4197930 | 0.81 | RAB9A (0.40) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4199997 | 0.80 | HTR1A (0.42) | USP2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4194844 | 0.80 | RAB9A (0.39) | SCDNPC1RAB9AMEN1KMT2A | |
| SCHEMBL4195581 | 0.78 | USP2 (0.52) | ALDH1A1USP2NPC1RAB9AMEN1 | |
| SCHEMBL6828236 | 0.77 | MEN1 (0.39) | ALDH1A1NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696909-A1 | BENZOTHIAZOLE DERIVATIVES FOR THE TREATMENT OF DIABETES | Applied Research Systems ARS Holding N.V. (AN) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005025567-A1 | BENZOTHIAZOLE DERIVATIVES FOR THE TREATMENT OF DIABETES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-03-24 | — | — | WO | disclosed |