Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | NAAA | Q02083 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4197930 | 0.88 | RAB9A (0.40) | RAB9ANPC1MEN1KMT2APDE10A | |
| SCHEMBL4195517 | 0.86 | DPP4 (0.40) | RAB9ANPC1MEN1KMT2APDE10A | |
| SCHEMBL4199975 | 0.85 | NPC1 (0.40) | RAB9ANPC1MEN1KMT2ADPP4 | |
| SCHEMBL6828236 | 0.83 | MEN1 (0.39) | RAB9ANPC1MEN1KMT2APDE10A | |
| SCHEMBL4197211 | 0.83 | SCN4A (0.38) | RAB9ANPC1MEN1KMT2ADPP4 | |
| SCHEMBL4197998 | 0.83 | NPC1 (0.53) | RAB9ANPC1MEN1KMT2APDE10A | |
| SCHEMBL4198007 | 0.83 | RAB9A (0.42) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4199997 | 0.81 | HTR1A (0.42) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4190547 | 0.80 | MAPK9 (0.39) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6017501 | 0.80 | ALDH1A1 (0.37) | RAB9ANPC1MEN1KMT2ASCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026802-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | Laboratoires Serono SA (CH) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007141224-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | LABORATOIRES SERONO SA (CH) | 2007-12-13 | — | — | WO | disclosed |