Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | HPD | P32754 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GRM8 | O00222 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6017684 | 1.00 | GPR35 (0.37) | GPR35PTPRCLMNAGAAALDH1A1 | |
| SCHEMBL9798929 | 0.88 | CYP3A4 (0.42) | GPR35PTPRCLMNAGAAALDH1A1 | |
| SCHEMBL8061160 | 0.83 | GPR35 (0.45) | GPR35PTPRCLMNAGAAALDH1A1 | |
| SCHEMBL3578389 | 0.82 | MEN1 (0.50) | LMNAALDH1A1MAPK1NPC1RAB9A | |
| SCHEMBL2028840 | 0.82 | LMNA (0.46) | PTPRCLMNAGAAALDH1A1MAPK1 | |
| SCHEMBL28033708 | 0.81 | NPSR1 (0.47) | GPR35GAAALDH1A1HTTTDP1 | |
| SCHEMBL2032819 | 0.80 | ALDH1A1 (0.42) | LMNAALDH1A1HTTTDP1POLB | |
| SCHEMBL78562 | 0.77 | ALDH1A1 (0.51) | PTPRCLMNAALDH1A1MAPK1NPC1 | |
| SCHEMBL10791330 | 0.77 | FBP1 (0.33) | PTPRCLMNAGAAALDH1A1NPC1 | |
| SCHEMBL2037217 | 0.75 | PTPRC (0.65) | PTPRCLMNAALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7029655-B2 | Magnetic resonance imaging agents for in vivo labeling and detection of amyloid deposits | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2006-04-18 | — | — | US | disclosed |
| WO-2002028441-A9 | MAGNETIC RESONANCE IMAGING AGENTS FOR IN VIVO LABELING AND DETECTION OF AMYLOID DEPOSITS | CALIFORNIA INST OF TECHN (US) | 2003-02-20 | — | — | WO | disclosed |
| US-20020098153-A1 | Magnetic resonance imaging agents for in vivo labeling and detection of amyloid deposits | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2002-07-25 | — | — | US | disclosed |
| WO-2002028441-A2 | MAGNETIC RESONANCE IMAGING AGENTS FOR IN VIVO LABELING AND DETECTION OF AMYLOID DEPOSITS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2002-04-11 | — | — | WO | disclosed |