Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11537274 | 0.60 | MEN1 (0.36) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25022126 | 0.59 | GAA (0.49) | MAPTALDH1A1POLBMEN1NPC1 | |
| SCHEMBL28186721 | 0.59 | HCAR1 (0.35) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1849574 | 0.59 | MIF (0.52) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL17220011 | 0.57 | ALDH1A1 (0.46) | MAPTHSD17B10ALDH1A1LMNARAB9A | |
| SCHEMBL30582304 | 0.57 | CA5A (0.48) | MAPTALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL18938467 | 0.57 | LMNA (0.44) | LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1375448 | 0.57 | CYP2A13 (0.37) | MAPTALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL27819863 | 0.57 | F2RL1 (0.47) | MAPTKCNN4ALDH1A1LMNAMEN1 | |
| SCHEMBL23064539 | 0.57 | ALDH1A1 (0.48) | MAPTALDH1A1LMNAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7071334-B2 | 6-(2-chloro-6-fluoro-phenyl)-triazolopyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2006-07-04 | — | — | US | claimed |
| EP-1381610-B1 | 6-(2-CHLORO-6-FLUORO-PHENYL)-TRIAZOLOPYRIMIDINES | BASF AG (DE) | 2004-08-25 | — | — | EP | claimed |
| US-20040110751-A1 | 6-(2-chloro-6-fluoro-phenyl)-triazolopyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2004-06-10 | — | — | US | claimed |
| EP-1381610-A1 | 6-(2-CHLORO-6-FLUORO-PHENYL)-TRIAZOLOPYRIMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2004-01-21 | — | — | EP | claimed |
| WO-2002083677-A1 | 6-(2-CHLORO-6-FLUORO-PHENYL)-TRIAZOLOPYRIMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-24 | — | — | WO | claimed |
| US-7071334-B2 | 6-(2-chloro-6-fluoro-phenyl)-triazolopyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2006-07-04 | — | — | US | disclosed |
| US-7071334-B2 | 6-(2-chloro-6-fluoro-phenyl)-triazolopyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2006-07-04 | — | — | US | disclosed |
| US-7071334-B2 | 6-(2-chloro-6-fluoro-phenyl)-triazolopyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2006-07-04 | — | — | US | disclosed |
| EP-1381610-B1 | 6-(2-CHLORO-6-FLUORO-PHENYL)-TRIAZOLOPYRIMIDINES | BASF AG (DE) | 2004-08-25 | — | — | EP | disclosed |
| EP-1381610-B1 | 6-(2-CHLORO-6-FLUORO-PHENYL)-TRIAZOLOPYRIMIDINES | BASF AG (DE) | 2004-08-25 | — | — | EP | disclosed |
| US-20040110751-A1 | 6-(2-chloro-6-fluoro-phenyl)-triazolopyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2004-06-10 | — | — | US | disclosed |
| US-20040110751-A1 | 6-(2-chloro-6-fluoro-phenyl)-triazolopyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2004-06-10 | — | — | US | disclosed |
| US-20040110751-A1 | 6-(2-chloro-6-fluoro-phenyl)-triazolopyrimidines | BASF AKTIENGESELLSCHAFT (DE) | 2004-06-10 | — | — | US | disclosed |
| EP-1381610-A1 | 6-(2-CHLORO-6-FLUORO-PHENYL)-TRIAZOLOPYRIMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2004-01-21 | — | — | EP | disclosed |
| EP-1381610-A1 | 6-(2-CHLORO-6-FLUORO-PHENYL)-TRIAZOLOPYRIMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2004-01-21 | — | — | EP | disclosed |
| WO-2002083677-A1 | 6-(2-CHLORO-6-FLUORO-PHENYL)-TRIAZOLOPYRIMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-24 | — | — | WO | disclosed |
| WO-2002083677-A1 | 6-(2-CHLORO-6-FLUORO-PHENYL)-TRIAZOLOPYRIMIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110751-A1 | 6-(2-chloro-6-fluoro-phenyl)-triazolopyrimidines | CBR3, CBR1, Q6ZSR9 | MAPT 3825/4885PHF8 2029/4885KCNN4 3278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.