Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30846729 | 1.00 | ADH1B (0.36) | ADH1BADH1CADH1ACNR2CNR1 | |
| SCHEMBL15338708 | 0.81 | ADH1B (0.36) | ADH1BADH1CADH1ATSHR | |
| SCHEMBL2775611 | 0.81 | CA2 (0.38) | ADH1BADH1CADH1ATSHR | |
| SCHEMBL771500 | 0.81 | CA2 (0.38) | ADH1BADH1CADH1ATSHR | |
| SCHEMBL7409346 | 0.80 | PDF (0.41) | ADH1BADH1CADH1A | |
| SCHEMBL7756606 | 0.78 | CNR2 (0.31) | CNR2CNR1 | |
| SCHEMBL14113439 | 0.77 | TSHR (0.44) | ADH1BADH1CADH1ACNR2CNR1 | |
| SCHEMBL9033596 | 0.77 | TSHR (0.44) | ADH1BADH1CADH1ACNR2CNR1 | |
| SCHEMBL7751859 | 0.77 | MMP3 (0.39) | — | |
| SCHEMBL16229642 | 0.75 | DPP4 (0.32) | CNR2CNR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7129059-B2 | Process for the preparation of compounds with enhanced optical purity | DSM IP ASSETS B.V. (NL) | 2006-10-31 | — | — | US | disclosed |
| US-20060127997-A1 | Process for the preparation of compounds with enhanced optical purity | QUAEDFLIEG PETER J L | 2006-06-15 | — | — | US | disclosed |
| EP-1141333-B1 | PROCESS FOR THE ENZYMATIC PREPARATION OF AMINO ACID DERIVATIVES WITH ENHANCED OPTICAL PURITY | DSM IP ASSETS BV (NL) | 2006-06-14 | — | — | EP | disclosed |
| EP-1013769-A1 | Process for the enzymatic preparation of amino acid derivatives with enhanced optical purity | DSM N.V. (NL) | 2000-06-28 | — | — | EP | disclosed |