Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14113439 | 1.00 | TSHR (0.44) | TSHRSMN1; SMN2ADH1BADH1CADH1A | |
| SCHEMBL13881311 | 0.83 | CTSK (0.33) | TSHRADH1BADH1CADH1ACA14 | |
| SCHEMBL7529008 | 0.82 | PKM (0.42) | TSHRPKM | |
| SCHEMBL15237906 | 0.80 | TSHR (0.47) | TSHRSMN1; SMN2 | |
| SCHEMBL15237905 | 0.77 | TSHR (0.48) | TSHRCA1CA2 | |
| SCHEMBL6018338 | 0.77 | ADH1B (0.36) | TSHRADH1BADH1CADH1ACNR1 | |
| SCHEMBL771500 | 0.77 | CA2 (0.38) | TSHRADH1BADH1CADH1ACA2 | |
| SCHEMBL15338708 | 0.77 | ADH1B (0.36) | TSHRADH1BADH1CADH1A | |
| SCHEMBL2775611 | 0.77 | CA2 (0.38) | TSHRADH1BADH1CADH1ACA2 | |
| SCHEMBL30846729 | 0.77 | ADH1B (0.36) | TSHRADH1BADH1CADH1ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705835-A1 | Quinoxalic-2,3-diones with an oxa or thiaheterocyclic fused ring | CIBA-GEIGY AG (CH) | 1996-04-10 | — | — | EP | disclosed |