Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 2/20 | 0.31 |
| ▸ | ALPI | P09923 | 1/20 | 0.31 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL549433 | 0.82 | LMNA (0.39) | ALDH1A1LMNAHDAC1HDAC2HDAC6 | |
| SCHEMBL8724482 | 0.81 | CTSD (0.43) | MAPTKDM4EALDH1A1LMNAHDAC3 | |
| SCHEMBL11681111 | 0.80 | PAOX (0.41) | ALDH1A1LMNAHDAC1HDAC2HDAC6 | |
| SCHEMBL12155314 | 0.80 | KMT2A (0.53) | KMT2AMAPTKDM4ETDP1ALDH1A1 | |
| SCHEMBL6127991 | 0.75 | CTSD (0.48) | KMT2AMAPTKDM4ETDP1ALDH1A1 | |
| SCHEMBL11311134 | 0.73 | ALDH1A1 (0.35) | ALDH1A1LMNABLM | |
| SCHEMBL5802104 | 0.72 | ALDH1A1 (0.54) | KMT2ATDP1ALDH1A1LMNAMEN1 | |
| SCHEMBL3933329 | 0.72 | KMT2A (0.67) | KMT2AMAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL14189780 | 0.72 | KMT2A (0.47) | KMT2AMAPTKDM4ETDP1ALDH1A1 | |
| SCHEMBL8745827 | 0.71 | KMT2A (0.65) | KMT2AMAPTKDM4ETDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060173107-A1 | Graftable hindered amine light stabilizers | CIBA SPECIALTY CHEMICALS CORP. | 2006-08-03 | — | — | US | disclosed |
| US-20030191242-A1 | Romp with oligomeric uv-absorbers | CIBA SPECIALTY CHEMICALS CORP. | 2003-10-09 | — | — | US | disclosed |
| EP-1263833-A1 | ROMP WITH OLIGOMERIC UV-ABSORBERS | Ciba SC Holding AG (CH) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001062821-A1 | ROMP WITH OLIGOMERIC UV-ABSORBERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-08-30 | — | — | WO | disclosed |
| US-6028131-A | Antioxidants containing phenol groups and aromatic amine groups | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-02-22 | — | — | US | disclosed |
| US-4125533-A | STABILIZERS | SANKYO CO. LTD. (JP) | 1978-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173107-A1 | Graftable hindered amine light stabilizers | IDO1, MAOA, TPH1 | KMT2A 744/4885MAPT 126/4885KDM4E 1124/4885 |
| US-20030191242-A1 | Romp with oligomeric uv-absorbers | OSTC, OCIAD1, OCIAD2 | KMT2A 4216/4885MAPT 473/4885KDM4E 4192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.