SCHEMBL6020932

SCHEMBL6020932

CN(C#N)C(=O)C(Cc1csc2ccccc12)NC(=O)c1ccccc1-c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSL P07711 1/20 0.47
CTSS P25774 1/20 0.47
CTSK P43235 1/20 0.47
F10 P00742 2/20 0.40
MMP2 P08253 1/20 0.39
MMP9 P14780 1/20 0.39
MMP8 P22894 1/20 0.39
CAPN1 P07384 1/20 0.38
OPRM1 P35372 2/20 0.38
OPRD1 P41143 2/20 0.38
OPRK1 P41145 2/20 0.38
TACR1 P25103 1/20 0.38
ITGB1 P05556 1/20 0.38
ITGA4 P13612 1/20 0.38
ITGB7 P26010 1/20 0.38
CLPP Q16740 2/20 0.38
CHRNB2 P17787 2/20 0.37
CHRNA4 P43681 2/20 0.37
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6019581 0.90 CTSL (0.48) CTSLCTSSCTSKF10MMP2
SCHEMBL6020920 0.89 CTSL (0.48) CTSLCTSSCTSKF10MMP2
SCHEMBL6019595 0.88 CTSL (0.46) CTSLCTSSCTSKF10MMP2
SCHEMBL6020711 0.87 CTSL (0.51) CTSLCTSSCTSKF10MMP2
SCHEMBL6019908 0.84 CTSL (0.43) CTSLCTSSCTSKF10MMP2
SCHEMBL6020505 0.83 CTSL (0.47) CTSLCTSSCTSKF10MMP2
SCHEMBL6019046 0.82 CTSL (0.56) CTSLCTSSCTSKF10MMP2
SCHEMBL6447376 0.82 ITGB1 (0.48) CTSLCTSSCTSKMMP9MMP8
SCHEMBL6019664 0.82 CTSL (0.49) CTSLCTSSCTSKF10MMP2
SCHEMBL6019638 0.81 TAAR1 (0.53) CTSLCTSSCTSKF10MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060252813-A1 Apparatus for curing a composite laminate JERINI AG (DE) 2006-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060252813-A1 Apparatus for curing a composite laminate DHX29, HDHD5, DHRS9 CTSL 2274/4885CTSS 2720/4885CTSK 2529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.