SCHEMBL6021049

SCHEMBL6021049

FC(F)(F)c1ccccc1On1cc[c]n1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCD O00767 6/20 0.34
HSD11B1 P28845 2/20 0.34
CYP3A4 P08684 2/20 0.34
CYP2D6 P10635 2/20 0.34
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
MAPK1 P28482 1/20 0.33
CYP2C19 P33261 1/20 0.33
PMP22 Q01453 1/20 0.33
KMT2A Q03164 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HTR1A P08908 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
ADRA2A P08913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2752010 0.83 MEN1 (0.31) CYP3A4CYP2D6MEN1ALDH1A1LMNA
SCHEMBL2752068 0.81 CES2 (0.34) HTR1A
SCHEMBL2753349 0.74 AR (0.30)
SCHEMBL2753883 0.73 SLC6A2 (0.35) HTR1ASLC6A2SLC6A4SLC6A3
SCHEMBL2752535 0.72 CA3 (0.31)
SCHEMBL17714126 0.71 LTA4H (0.32) LTA4H
SCHEMBL2751484 0.70 TRPA1 (0.33) HTR1ASLC6A2SLC6A4SLC6A3
SCHEMBL2753360 0.70 ALDH1A1 (0.36) CYP3A4CYP2D6ALDH1A1CYP1A2CYP2C19
SCHEMBL2751871 0.70 MAPT (0.37) CYP3A4CYP2D6MEN1ALDH1A1LMNA
SCHEMBL2751917 0.69 GAA (0.36) MEN1ALDH1A1MAPTKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1622905-A1 IMIDAZOPYRIDINE INTERMEDIATES ALTANA Pharma AG (DE) 2006-02-08 EP disclosed
WO-2004099203-A1 IMIDAZOPYRIDINE INTERMEDIATES ALTANA PHARMA AG (DE) 2004-11-18 WO disclosed