Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.58 |
| ▸ | L3MBTL3 | Q96JM7 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5047484 | 0.81 | MGLL (0.62) | MGLLL3MBTL3L3MBTL1ALDH1A1TP53 | |
| SCHEMBL5047494 | 0.81 | ACHE (0.67) | MGLLL3MBTL3L3MBTL1ALDH1A1TP53 | |
| SCHEMBL1947109 | 0.79 | HPGD (0.65) | MGLLL3MBTL3L3MBTL1ALDH1A1TP53 | |
| SCHEMBL12547325 | 0.79 | SMN1; SMN2 (0.63) | MGLLL3MBTL3L3MBTL1ALDH1A1TP53 | |
| SCHEMBL7906862 | 0.77 | HPGD (0.66) | MGLLL3MBTL3L3MBTL1ALDH1A1TP53 | |
| SCHEMBL22516911 | 0.77 | MGLL (0.57) | MGLLL3MBTL3L3MBTL1ALDH1A1TP53 | |
| SCHEMBL10724068 | 0.75 | L3MBTL3 (0.59) | MGLLL3MBTL3L3MBTL1ALDH1A1TP53 | |
| SCHEMBL4703093 | 0.75 | KDM4E (0.54) | TP53 | |
| SCHEMBL14107680 | 0.75 | SIGMAR1 (0.65) | MGLLALDH1A1TP53 | |
| SCHEMBL2476582 | 0.75 | L3MBTL1 (0.62) | MGLLL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732534-A1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | Applied Research Systems ARS Holding N.V. (AN) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005082347-A1 | USE OF METHYLENE AMIDE DERIVATIVES IN CARDIOVASCULAR DISORDERS | APLLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2005-09-09 | — | — | WO | disclosed |