Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6023885 | 0.84 | SIGMAR1 (0.53) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6024499 | 0.83 | SIGMAR1 (0.52) | SIGMAR1 | |
| Maleic Acid SCHEMBL6023259 | 0.75 | SIGMAR1 (0.47) | SIGMAR1 | |
| Fumaric Acid SCHEMBL6023402 | 0.75 | SIGMAR1 (0.47) | SIGMAR1 | |
| SCHEMBL6024171 | 0.74 | TAS1R3 (0.51) | SIGMAR1TAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL6024287 | 0.73 | TAS1R3 (0.50) | SIGMAR1TAS1R3TAS1R1 | |
| SCHEMBL13484112 | 0.72 | PTGS1 (0.54) | RAD52PAX8SLC2A1 | |
| SCHEMBL28033428 | 0.71 | BDKRB2 (0.45) | RAD52PAX8SLC2A1 | |
| SCHEMBL4672629 | 0.71 | SLC2A1 (0.72) | RAD52PAX8SLC2A1 | |
| SCHEMBL6024641 | 0.71 | SIGMAR1 (0.73) | SIGMAR1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0957080-B1 | NOVEL ETHYLAMINE DERIVATIVES | FUJIMOTO BROTHERS CO LTD (JP) | 2006-06-21 | — | — | EP | claimed |
| US-6214859-B1 | PSYCHOLOGICAL DISORDERS; ALZHEIMER'S DISORDERS; PARKINSON'SDISORDERS | FUJIMOTO BROTHERS CO., LTD. (JP) | 2001-04-10 | — | — | US | claimed |
| EP-0957080-A1 | NOVEL ETHYLAMINE DERIVATIVES | Fujimoto Brothers Co., Ltd. (JP) | 1999-11-17 | — | — | EP | claimed |