Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 13/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727795 | 0.78 | ACHE (0.32) | ACHE | |
| SCHEMBL3809933 | 0.78 | — | — | |
| SCHEMBL3810910 | 0.78 | HCRTR2 (0.30) | — | |
| SCHEMBL5046422 | 0.77 | P2RX7 (0.30) | — | |
| SCHEMBL3818944 | 0.77 | — | — | |
| SCHEMBL6883487 | 0.77 | — | — | |
| SCHEMBL3818365 | 0.75 | CTSL (0.31) | — | |
| SCHEMBL27485317 | 0.75 | TSHR (0.39) | — | |
| SCHEMBL27554172 | 0.73 | HCRTR2 (0.41) | EPHX1 | |
| SCHEMBL6024135 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1677812-A2 | TREATING OR PREVENTING RESTLESS LEGS SYNDROME USING PRODRUGS OF GABA ANALOGS | Xenoport, Inc. (US) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005027850-A2 | TREATING OR PREVENTING RESTLESS LEGS SYNDROME USING PRODRUGS OF GABA ANALOGS | XENOPORT, INC. (US) | 2005-03-31 | — | — | WO | disclosed |