Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6024135 | 0.88 | — | — | |
| SCHEMBL27485317 | 0.82 | TSHR (0.39) | P2RX7 | |
| SCHEMBL27554172 | 0.80 | HCRTR2 (0.41) | P2RX7 | |
| SCHEMBL1727795 | 0.80 | ACHE (0.32) | P2RX7 | |
| SCHEMBL3813044 | 0.78 | P2RX7 (0.31) | P2RX7 | |
| SCHEMBL3808910 | 0.78 | CTSK (0.30) | — | |
| SCHEMBL3813627 | 0.78 | HCRTR2 (0.32) | — | |
| SCHEMBL6023653 | 0.77 | NAAA (0.41) | — | |
| SCHEMBL27484249 | 0.76 | SLC6A4 (0.33) | — | |
| SCHEMBL597825 | 0.76 | ALDH1A1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608357-A4 | TREATING OR PREVENTING HOT FLASHES USING PRODRUGS OF GABA ANALOGS | XENOPORT INC (US) | 2008-03-26 | — | — | EP | disclosed |
| EP-1608357-A2 | TREATING OR PREVENTING HOT FLASHES USING PRODRUGS OF GABA ANALOGS | Xenoport, Inc. (US) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004089289-A2 | TREATING OR PREVENTING HOT FLASHES USING PRODRUGS OF GABA ANALOGS | XENOPORT, INC. (US) | 2004-10-21 | — | — | WO | disclosed |