Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP8 | P22894 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 4/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29646020 | 0.77 | KDM1A (0.43) | ANPEPGRIN2DGRIN3BGRIN1GRIN2A | |
| Formamide SCHEMBL9732052 | 0.75 | PRCP (0.36) | ANPEPAURKARPS6KB1KDM1A | |
| SCHEMBL29127675 | 0.74 | SIGMAR1 (0.41) | KDM1A | |
| SCHEMBL9732048 | 0.73 | NAMPT (0.32) | MMP1MMP2MMP9MMP8AURKA | |
| SCHEMBL8017605 | 0.73 | NAMPT (0.43) | MMP1MMP2MMP9MMP8AURKA | |
| SCHEMBL13783748 | 0.73 | NAMPT (0.43) | MMP1MMP2MMP9MMP8AURKA | |
| SCHEMBL8050161 | 0.73 | NAMPT (0.43) | MMP1MMP2MMP9MMP8AURKA | |
| SCHEMBL8013654 | 0.73 | NAMPT (0.43) | MMP1MMP2MMP9MMP8AURKA | |
| SCHEMBL8364875 | 0.73 | PRCP (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3867845 | 0.73 | ANPEP (0.42) | ANPEPGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7129263-B2 | Preparation of 3-azabicyclo [3.1.0] hexane derivatives | PFIZER INC. | 2006-10-31 | — | — | US | disclosed |
| EP-1675829-A1 | PREPARATION OF 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES | Pfizer Products Inc. (US) | 2006-07-05 | — | — | EP | disclosed |
| US-20050113437-A1 | Preparation of 3-azabicyclo [3.1.0] hexane derivatives | PFIZER INC. | 2005-05-26 | — | — | US | disclosed |
| WO-2005037790-A1 | PREPARATION OF 3-AZABICYCLO [3.1.0] HEXANE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2005-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113437-A1 | Preparation of 3-azabicyclo [3.1.0] hexane derivatives | ADH1C, ADH1A, ADH5 | ANPEP 3702/4885MMP1 4281/4885MMP2 4848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.