Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 9/20 | 0.41 |
| ▸ | NOS1 | P29475 | 9/20 | 0.41 |
| ▸ | NOS2 | P35228 | 5/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6023363 | 0.86 | NOS3 (0.41) | NOS3NOS1NOS2 | |
| SCHEMBL6022573 | 0.85 | NOS3 (0.40) | NOS3NOS1NOS2 | |
| SCHEMBL4310929 | 0.82 | ALDH1A1 (0.49) | NOS3NOS1 | |
| SCHEMBL6023924 | 0.82 | MAPT (0.42) | DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL4315282 | 0.82 | ALDH1A1 (0.48) | NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL6024148 | 0.81 | MAPT (0.43) | — | |
| SCHEMBL13979808 | 0.74 | NOS3 (0.62) | NOS3NOS1NOS2 | |
| SCHEMBL7562881 | 0.72 | QRFPR (0.53) | NOS3NOS1NOS2 | |
| SCHEMBL4323025 | 0.71 | LMNA (0.49) | NOS3NOS1 | |
| SCHEMBL6968842 | 0.71 | NOS1 (0.57) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030162789-A1 | 4-Hydroxycinnamamide derivatives as antioxidants and pharmaceutical compositions containing them | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2003-08-28 | — | — | US | claimed |
| US-7078407-B2 | 4-hydroxycinnamamide derivatives as antioxidants and pharmaceutical compositions containing them | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-07-18 | — | — | US | disclosed |
| US-20030162789-A1 | 4-Hydroxycinnamamide derivatives as antioxidants and pharmaceutical compositions containing them | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162789-A1 | 4-Hydroxycinnamamide derivatives as antioxidants and pharmaceutical compositions containing them | HTT, PARK7, NQO1 | NOS3 2966/4885NOS1 3761/4885NOS2 3854/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.